Peter van der Gulik
- Full Name
- Drs. P.T.S. van der Gulik
- Function(s)
- Project member
- Peter.van.der.Gulik@cwi.nl
- Telephone
- +31 20 592 4232
- Room
- L232
- Department(s)
- Algorithms and Complexity, Information & Documentation
Biography
Peter T. S. van der Gulik is a researcher at the Centrum Wiskunde & Informatica in Amsterdam, in the research group Algorithms and Complexity. Peter is working on problems at the interface of biology and computer science. He is interested in structure and origin of the genetic code, conserved hydrogen bonds and conserved hydrophobic interactions in protein folding, the role in the primordial cell of the first coded oligopeptide, and Asgardarchaeal tRNA sets. Up to 2020, Peter van der Gulik is co-author of eight peer-reviewed articles: PMID 19761777, PMID 21358008, PMID 22076654, PMID 23877342, PMID 24178388, PMID 25607813, PMID 27454314 and PMID 28927381; and author of peer-reviewed article PMID 26580656. He defended his Ph.D. thesis, Considerations in Evolutionary Biochemistry (ISBN 978-94-028-1569-6), on September 18, 2019. Prof. dr. Harry Buhrman (QUSOFT, Universiteit van Amsterdam and CWI) and prof. dr. Wouter Hoff (Oklahoma State University) are his thesis advisors, and dr. Dave Speijer (Amsterdam UMC and Universiteit van Amsterdam) is Peter's thesis co-advisor.
Publications
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van der Gulik, P.T.S. (2019, September 18). Considerations in evolutionary biochemistry. ILLC Dissertation Series.
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van der Gulik, P.T.S, Hoff, W.D, & Speijer, D. (2017). In defence of the three-domains of life paradigm. BMC Evolutionary Biology, 17. doi:10.1186/s12862-017-1059-z
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van der Gulik, P.T.S, & Hoff, W.D. (2016). Anticodon modifications in the tRNA set of LUCA and the fundamental regularity in the Standard Genetic Code. PLoS ONE, 11(7). doi:10.1371/journal.pone.0158342
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van der Gulik, P.T.S. (2015). On the Origin of Sequence. Life, 5(4), 1629–1637. doi:10.3390/life5041629
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van der Gulik, P.T.S, & Speijer, D. (2015). How Amino Acids and Peptides Shaped the RNA World. Life, 5(1), 230–246.
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Buhrman, H.M, van der Gulik, P.T.S, Klau, G.W, Schaffner, C, Speijer, D, & Stougie, L. (2013). A Realistic Model Under Which the Genetic Code is Optimal. Journal of Molecular Evolution, 77(4), 170–184. doi:10.1007/s00239-013-9571-2
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Buhrman, H.M, van der Gulik, P.T.S, Kelk, S.M, Koolen-Wijkstra, W.M, & Stougie, L. (2011). Some mathematical refinements concerning error minimization in the genetic code. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 11, 1358–1372.
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van der Gulik, P.T.S, & Hoff, W.D. (2011). Unassigned Codons, Nonsense Suppression, and Anticodon Modifications in the Evolution of the Genetic Code. Journal of Molecular Evolution, 73(combined 3-4), 59–69.
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van der Gulik, P.T.S, Massar, S, Gilis, D, Buhrman, H.M, & Rooman, M. (2009). The first peptides: The evolutionary transition between prebiotic amino acids and early proteins. Journal of Theoretical Biology, 261(4), 531–539.