This research is part of the research programme Open Technology Programme
with project number 15586, which is financed by the Dutch Research Council (NWO),
Elekta, and Xomnia. Further, the work is co-funded by the public-private partnership
allowance for top consortia for knowledge and innovation (TKIs) from the Dutch
Ministry of Economic Affairs. The research has been carried out in collaboration with
the Amsterdam UMC, location Academic Medical Center (AMC) and Leiden University
Medical Center (LUMC), Netherlands.
We thank Jan Wiersma (Amsterdam UMC location AMC, The Netherlands), Jeroen
de Vries (Amsterdam UMC location AMC, The Netherlands), and Bart van de Poel
(Xomnia B.V., The Netherlands) for their contributions in obtaining the data, data
curation, and data cleaning, respectively, in the initial stage of the project work in
Chapter 4. We thank W. Visser-Groot and S.M. de Boer (Leiden University Medical
Center, The Netherlands) for their contributions to the work in Chapter 6.
SIKS Dissertation Series No. 2025-16
The research reported in this thesis has been carried out under the auspices of SIKS, the
Dutch Research School for Information and Knowledge Systems.
promotors:
Rector Magnificus voorzitter
prof. dr. P.A.N. Bosman Technische Universiteit Delft, NL;
Centrum Wiskunde & Informatica, NL
dr. T. Alderliesten Leids Universitair Medisch Centrum, NL;
Technische Universiteit Delft, NL
dr. G. H. Westerveld, MD Erasmus Medisch Centrum, NL