Description

Leader of the group Life Sciences and Health: Leen Stougie.

Our research group creates fundamental knowledge and applied solutions in the broad field of life sciences. We promote understanding of how biological processes work in detail. Our interdisciplinary team of computer scientists, mathematicians and theoretical biologists develops new models, theories, and decision support systems in collaboration with experimental biologists and medical experts. We are motivated by applications of our work in practice

 

Watch our group video to get a glimpse of our activities or click here for more information about our group structure.

 

News

Cells’ own contractions stimulate growth orientation

Cells’ own contractions stimulate growth orientation

During the growth of embryos cells align with forces from the surrounding tissue. These forces originate from differences in growth rates, muscle contractions or gravity. Mathematicians at the CWI research centre in Amsterdam now showed for the first time that active cell contractions can accelerate and facilitate this reorientation of cells. Their research was recently published in the leading Biophysical Journal (112).

Cells’ own contractions stimulate growth orientation - Read More…

Current events

PhD defense Ngoc Hoang Luong (LSH)

  • 2018-10-17T15:00:00+02:00
  • 2018-10-17T16:00:00+02:00
October 17 Wednesday

Start: 2018-10-17 15:00:00+02:00 End: 2018-10-17 16:00:00+02:00

Senaatszaal of the Auditorium (Aula), Delft University of Technology, Mekelweg 5, Delft

Everyone is invited to attend the public defense of Ngoc Hoang Luong of his PhD thesis:

Design and Application of Scalable Evolutionary Algorithms in Electricity Distribution Network Expansion Planning

Promotoren: prof.dr. Han La Poutré and prof.dr. Peter Bosman

 

Summary of the dissertation is here.

LSH Seminar Professor Kalyanmoy Deb (Michigan State University)

  • 2018-10-18T14:00:00+02:00
  • 2018-10-18T15:00:00+02:00
October 18 Thursday

Start: 2018-10-18 14:00:00+02:00 End: 2018-10-18 15:00:00+02:00

CWI, L120

Speaker:
Kalyanmoy Deb, Koenig Endowed Chair Professor
Michigan State University, East Lansing, USA, kdeb@egr.msu.edu

Title:
Breaking the Billion-Variable Barrier Using Customized Evolutionary Optimization

Abstract:
Optimization methods and practices are around for more than 50 years, but they are still criticized for their "curse of dimensionality". In this talk, we shall look at a specific large-dimensional integer-valued resource allocation problem class from practice and review the performance of well-known softwares, such as IBM's CPLEX, on the problem. Thereafter, we shall present a population-based heuristic search algorithm that has the ability to recombine short-sized building blocks, despite having overlapping variable linkage, to form larger-sized building blocks. The process is eventually able to solve a billion-variable version of the problem to near-optimality in polynomial computational time, making the application one of the largest size optimization problems ever solved.

Bio-sketch of the Speaker:
Kalyanmoy Deb is Koenig Endowed Chair Professor at Department of Electrical and Computer Engineering in Michigan State University, USA. Prof. Deb's research interests are in evolutionary optimization and their application in multi-criterion optimization, modeling, and machine learning. He has worked at various universities across the world including IITs in India, University of Dortmund and Karlsruhe Institute of Technology in Germany, Aalto University in Finland, University of Skovde in Sweden, Nanyang Technological University in Singapore. He was awarded Infosys Prize, TWAS Prize in Engineering Sciences, CajAstur Mamdani Prize, Distinguished Alumni Award from IIT Kharagpur, Edgeworth-Pareto award, Bhatnagar Prize in Engineering Sciences, and Bessel Research award from Germany. He has been awarded IEEE CIS's "EC Pioneer Award". He is fellow of IEEE, ASME, and three Indian science and engineering academies. He has published over 490 research papers with Google Scholar citation of over 117,000 with h-index 110. He is in the editorial board on 18 major international journals. More information about his research contribution can be found from http://www.egr.msu.edu/~kdeb.

Space is limited so please register for this seminar.

Members

Associated Members

Publications

Software

Current projects with external funding

  • 3D dose reconstruction for children with long-term follow-up Toward improved decision making in radiation treatment for children with cancer
  • Enhancing protein-drug binding prediction
  • ICT based Innovations in the Battle against Cancer – Next - Generation Patient -Tailored Brachytherapy Cancer Treatment Planning
  • Improving Childhood Cancer Care when Parents Cannot be There - Reducing Medical Traumatic Stress in Childhood Cancer Patients by Bonding with a Robot Companion
  • Statistical Models for Structural Genetic Variants in the Genome of the Netherlands
  • Identificatie van homogene subgroepen bij mensen met een chronische ziekte, die ernstig vermoeid zijn, door middel van een persoonsgerichte studie opzet. (Beter Gezond)
  • Fusible Evolutionary Deep Neural Network Mixture Learning from Distributed Data for Robust Medical Image Analysis (FEDMix)
  • Multi-Objective Deformable Image Registration (MODIR) – An Innovative Synergy of Multi-Objective Optimization, Machine Learning, and Biomechanical Modeling for the Registration of Medical Images with (MODIR)

Related partners

  • AMC Medical Research
  • Elekta Limited
  • Nucletron Operations BV
  • Xomnia
  • Academisch Medisch Centrum
  • Biomedical Imaging Group Rotterdam
  • Erasmus Universiteit Rotterdam
  • KiKa
  • Technische Universiteit Delft
  • Universiteit Leiden