LSH Seminar Alejandro Lopez Rincon

Human Motion as a Complex System

Alejandro Lopez Rincon

Title: Human Motion as a Complex System

Abstract: Movement of the human body is the result of complex processes involving several subsystems. Motion execution is generated by electrical impulses in the motor cortex, which propagate through the nervous system until reaching the alpha neurons associated with the specific activation of a particular group of muscle fibers. Several studies have shown that post-stroke patients develop higher activity in the sensorimotor areas of the affected hemisphere of the brain compared to healthy people during motor tasks. A proper understanding of the activity in the brains in post-stroke patients will help us develop mathematical models that clarify the underlying mechanisms associated with movement.

This research describes an anatomically based brain computer model of movement impairment in stroke patients, providing an understanding of the mechanisms of neuromuscular complications. The overall system is composed by the abstraction of the following three subsystems: the brain, the skeletal muscle, and a cable equation that connects both systems modeled using a bidomain approach with the finite element method to simulate it. Two scenarios were simulated: a healthy subject and a post-stroke patient with motion impairment to create activity maps and compared them with the measurements.