Roeland Merks

Scientific Staff Member, Professor

Full Name Prof.dr. R.M.H. Merks
Function(s) Scientific Staff Member, Professor
Telephone +31 20 592 4117
Room M276
Department(s) Life Sciences


Merks' research focuses on cell-based, multiscale modeling of plant development and angiogenesis. His team (currently 1 postdoc, 4 PhD students, 2 MSc students) works on plant development, angiogenesis, gut microbiota metabolism in close collaboration with experimental and theoretical groups elsewhere. In 2010 Merks was awarded an NWO Vidi (Interdisciplinary-ALW) to further develop his work on angiogenesis, focusing on the interactions between endothelial cells and the extracellular matrix.

Selected Publications

  • F. Tessadon, E.S. Noël, E.G. Rens, R. Magliozzi, I.J.A. Evers-Van Gogh, D. Guardavaccaro, Roeland Merks, J. Bakkers, Nodal Signaling Range Is Regulated by Proprotein Convertase-Mediated Maturation, 631-639, 2015
  • S.E.M. Boas, Roeland Merks, Tip cell overtaking occurs as a side effect of sprouting in computational models of angiogenesis, BioMed Central, 2015
  • D. Palachanis, A. Szabó, Roeland Merks, Particle-based simulation of ellipse-shaped particle aggregation as a model for vascular network formation, Springer, 1-9, 2015
  • R.F.M. van Oers, E.G. Rens, D.J. LaValley, C. Reinhart-King, Roeland Merks, Mechanical Cell-Matrix Feedback Explains Pairwise and Collective Endothelial Cell Behavior In Vitro, PLoS, 2014
  • M.M. Palm, Roeland Merks, Vascular networks due to dynamically arrested crystalline ordering of elongated cells , American Physical Society, 2013
  • M.J.A. van Hoek, Roeland Merks, Redox balance is key to explaining full vs. partial switching to low-yield metabolism, BioMed Central, 2012
  • Roeland Merks, E.D. Perryn, A. Shirinifard, J.A. Glazier, Contact-inhibited chemotaxis in de novo and sprouting blood-vessel growth, PLoS, e1000163-last, 2008


  • Reconstructing the interactions between cells and extracellular matrix during angiogenesis