Speaker: Stephan van Gils
Title: Some aspects of dynamics within the basal ganglia 

Abstract: Networks of excitatory and inhibitory neurons are responsible for
the generation of rhythms. An example is the basal ganglia, a group of
nuclei that play a key role in the organization of movement. Under
pathological conditions, for instance a lack of Dopamine, dysfunction of
basal ganglia is associated with movement disorders such as Parkinson's
disease. We consider a computational model for a thalamic relay neuron in
relation to pathological input. The effect of Deep Brain Stimulation is
explained in a reduced model. As a first step toward integration of
measurements into our modeling, we show results of micro recordings in the
subthalamic nucleus in patients undergoing deep brain surgery.

Date: 14 April 2009
Time: 10.30-11.30h, tea starting at 10h
Room: M279